UCSD HEALTH SCIENCES-RELATED CORE FACILITIES - February 24, 2004
Staff Contact :
Teresa Hsiao ( thsiao@ucsd.edu ) (858: 534-7885) (Financial Analyst)
Faculty Contact :
David N. Bailey, M.D. ( dnbailey@ucsd.edu ) (858: 822-5577) (Deputy Vice Chancellor for Health Sciences)
ALZHEIMER'S DISEASE ASSESSMENT UNIT (NEUROSCIENCES)
(DR. LEON THAL)
Location: 8950 Villa La Jolla (La Jolla Professional Building)
Contact: Mike Bartel ( mbartel@ucsd.edu ) (858: 534-8854)
This unit provides a standardized assessment test for Alzheimer's disease.
ANATOMIC PATHOLOGY SERVICES (PATHOLOGY)
(DR. NOEL WEIDNER)
Location: UCSD Medical Center – Hillcrest and Thornton
Contact: Judy Tieber ( jtieber@ucsd.edu ) (858: 534-4325)
These services include surgical pathology, cytopathology, neuropathology, and hematopathology.
ANIMAL GENETICS CORE FACILITY (MEDICINE-RDCC)
(DR. MARY CORR)
Location: Rooms 126C, 139, Stein Clinical Sciences Building
Contact: Dr. Mary Corr ( mpcorr@ucsd.edu ) (858: 534-7817)
This unit facilitates the generation of essential strains of mice for research in rheumatic diseases.
BIOCHEMICAL GENETICS LAB (PEDIATRICS)
(DR. WILLIAM NYHAN)
Location: Room 203, 220 Dickinson Street (UCSD Medical Center-Hillcrest)
Contact: Bonnie Holmes ( bholmes@ucsd.edu ) (619: 543-5286)
This lab performs metabolic screening, amino acid analysis, and organic acid analysis.
BIOGEM (BIOMEDICAL GENOMICS MICROARRAY FACILITY) (SOM DEAN'S OFFICE)
(DR. GARY HARDIMAN)
Location: Rooms 1500 and 2002, Bonner Hall (to be relocated to Leichtag Building)
Contact: Deborah Seidle ( dseidle@ucsd.edu ) (858: 534-7577)
Labeled RNA and DNA targets (e.g. messenger RNA obtained from cells, tissues, or organisms under different conditions) are analyzed by hybridization on high-density
DNA chips, permitting genome scale transcriptional profiling.
BIOMARKER CORE FACILITY (MEDICINE-RDCC)
(DR. GARY FIRESTEIN)
Location: Fifth Floor, Basic Sciences Building
Contact: Dr. Gary Firestein ( gfirestein@ucsd.edu ) (858: 822-0480)
This facility provides specialized support to measure biomarkers in patients and in animal models of inflammation and autoimmunity.
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BIOPHYSICS INSTRUMENTATION FACILITY (CHEMISTRY AND BIOCHEMISTRY)
(DR. ELIZABETH KOMIVES)
Location: Room 2237, Urey Hall
Contact: Dr. Elizabeth Komives ( ekomives@ucsd.edu ) (858: 534-3058)
This facility is a resource providing instrumentation for analysis of macromolecular interaction, binding, and kinetics.
BIOSTATISTICS AND INFORMATICS LAB (FAMILY & PREVENTIVE MEDICINE)
(DR. RON THOMAS)
Location: Rooms 107, 110, 111, Beech Building
Contact: Sean Clark ( jclark@ucsd.edu ) (858: 822-4901)
This lab provides biostatistical consulting and informatics services.
BIOSTATISTICS UNIT (CANCER CENTER)
(DR. JOHN PIERCE)
Location: Room 104, Beech Building
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This unit provides data and biostatistical analysis.
CENTER FOR MOLECULAR IMAGING
(DRS. CARL HOH, CLINICAL PET; DR. WILLIAM ECKELMAN, RADIOLIGAND PROGRAM)
Location: 11388 Sorrento Valley Road, Suite 100 , San Diego , CA 92121
Contact: Michelle Nazarian (858: 658-6877)
This center provides clinical positron emission tomography (PET) services using a Siemens HR+ (to be upgraded to a 16-slice GE ST PET-CT on April 1, 2004). It will provide FDG-PET for rodents when the GE/Suinsa double ring micro-PET is installed in June 2004. A cyclotron is present onsite for short-lived isotopes such as C-11 (for neuroscience studies) and N-13 ammonia (for cardiac perfusion studies).
CLINICAL LABORATORY SERVICES (PATHOLOGY)
(DR. ANNA DREILINGER)
Location: Clinical Laboratories of UCSD Medical Center-Hillcrest and Thornton
Contacct: Judy Tieber ( jtieber@ucsd.edu ) (858: 534-4325)
These laboratories provide an array of analytical services (chemistry, hematology, microbiology, immunology) primarily for clinical purposes but also available to researchers.
COMPARATIVE NEUROMUSCULAR LAB (PATHOLOGY)
(DR. DIANE SHELTON)
Location: Second Floor, Basic Sciences Building
Contact: Nikita Rochelle ( nrochelle@ucsd.edu ) (858: 822-0198)
This lab performs unique diagnostic testing for neuromuscular disorders affecting domestic animals.
COMPARATIVE NEUROPATHOLOGY LAB (PATHOLOGY)
(DR. DIANE SHELTON)
Location: Room 2095, Basic Sciences Building
Contact: Nikita Rochelle ( nrochelle@ucsd.edu ) (858: 822-0198)
This lab provides muscle and peripheral nerve histology, histochemistry, and immunohistochemistry analyses as well as serum assays.
CORE BIO SERVICES (SOM DEAN'S OFFICE)
(DR. JERRY SCHNEIDER)
Location: Room B223, Basic Sciences Building
Contact: Deborah Seidle ( dseidle@ucsd.edu ) (858: 534-7577)
This facility provides a wide variety of cellular and molecular biology products and services.
CYSTINE DETERMINATION LAB (PEDIATRICS)
(DR. JERRY SCHNEIDER)
Location: Room 4003, Basic Sciences Building
Contact; Deborah Seidle ( dseidle@ucsd.edu ) (858: 534-7577)
This lab performs cystine analysis.
CYTOGENETICS LAB (MEDICINE)
(DR. MARIE DELL' AQUILA)
Location: IMG Facility
Contact: Dr. Marie Dell'Aquila ( mdellaquila@ucsd.edu ) (858: 534-4308)
This lab performs amniotic fluid analysis, lymphocyte chromosome analysis, and karyotyping services.
DIGITAL IMAGING & MICROINJECTION FACILITY (CANCER CENTER)
(DR. JAMES FERAMISCO)
Location: Room 122C, Center for Molecular Genetics (CMM-East pending)
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This facility provides deconvolution, brightfield, phase/contrast, and DIC microscopy plus image analysis in conjunction with the San Diego Supercomputer Center. It also provides somatic cell microinjection services.
DNA SEQUENCING UNIT (CANCER CENTER)
(DR. LINDA WASSERMAN)
Location: Room 238, CMM-West
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This unit provides DNA sequencing reactions and gel analysis.
DRUG ASSAY AND PHARMACEUTICAL LAB (PEDIATRICS)
(DR. JAMES CONNOR)
Location: Room B112, Clinical Teaching Facility, Wing B
Contact: Carol Latham ( c1latham@ucsd.edu ) (619: 543-6944)
This lab drug assays and provides pharmacokinetics and pharmacodynamices support services for antiviral agents.
ELECTRON MICROSCOPY FACILITY (PATHOLOGY)
(DR. HENRY C. POWELL)
Location: Room 2047, Basic Sciences Building ; UCSD Medical Center-Hillcrest
Contact: Dr. Henry C. Powell ( hpowell@ucsd.edu ) (858: 534-3717)
This facility provides an array of electron microscopy services.
FERTILITY LAB (SURGERY/UROLOGY)
(DR. LOWELL PARSONS)
Location: Room 109, Surgery Research Laboratory Building (UCSD Medical
Center – Hillcrest)
Contact: Nancy Roberts ( ncroberts@ucsd.edu ) (619: 543-6711)
This lab performs semen analysis, anti-sperm antibody testing, and sperm washing.
FLOW CYTOMETRY, DIAGNOSTIC (PATHOLOGY)
(DR. H. ELIZABETH BROOME)
Location: UCSD Medical Center-Hillcrest
Contact: Judy Tieber ( jtieber@ucsd.edu ) (858: 534-4325)
This facility provides analysis of T-cell ubsets, leukemia and lymphoma panels, and stem-cell enumeration.
FLOW CYTOMETRY FACILITY ( CANCER CENTER )
(DR. THOMAS KIPPS)
Location: 126, Building #4
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This facility provides cell-sorting services.
FUNCTIONAL MAGNETIC RESONANCE CENTER (RADIOLOGY)
(DR. RICHARD BUXTON)
Location: Keck Building
Contact: Wei Deng ( wedeng@ucsd.edu ) (858: 822-0527)
This center provides anatomical and functional magnetic resonance imaging capabilities for animal and human subjects.
GLYCOBIOLOGY CORE FACILITY (GLYCOBIOLOGY TRAINING AND RESEARCH CENTER )
(DR. HERMAN VAN HALBEEK)
Location: First Floor, CMM-East
Contact: Stephen Lopez ( slopez@ucsd.edu ) (858: 534-7710)
This facility provides carbohydrate structural and monosaccharide analyses.
HEALTH OUTCOMES ASSESSMENT UNIT (FAMILY & PREVENTIVE MEDICINE)
(DR. TED GANIATS)
Location: 8950 Villa La Jolla ( La Jolla Professional Center )
Contact: Carol Davis ( cdavis@ucsd.edu ) (619: 549-5488)
This unit provides services related to an instrument for assessing quality of life index.
HISTOLOGY/HYBRIDOMA CORE FACILITY ( CANCER CENTER )
(DR. NISSI VARKI)
Location: 1080 CMM-East
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This facility provides histologic, immunohistochemical, technical, and interpretative services.
HORMONE ASSAY FACILITY (ANESTHESIOLOGY)
(DR. TONY YAKSH)
Location: CTF C303
Contact: Dr. Steven Rossi ( ssrossi@ucsd.edu ) (619: 543-5563)
This facility provides assays of a variety of hormones, drugs, and anesthetic agents.
IDENTIFICATION OF SPECIAL ANTIBODIES (PATHOLOGY)
( DR. THOMAS LANE )
Location: Blood Bank, UCSD Medical Center-Hillcrest
Contact: Judy Tieber ( jtieber@ucsd.edu ) (858: 534-4325)
This service assesses the presence of anti-red cell antibodies.
INFORMATION TECHNOLOGY SERVICES ( CANCER CENTER )
(DR. RICHARD DETERESA)
Location: Rooms 122, 123, and 144, Guava Building
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This service provides information technology support to Cancer Center members.
INTERPRETATIVE PATHOLOGY (PATHOLOGY)
(DR. NOEL WEIDNER)
Location: Room 2-120, UCSD Medical Center-Hillcrest
Contact: Judy Tieber ( jtieber@ucsd.edu ) (858: 534-4325)
This service includes tissue and cytologic diagnosis, in situ immunohistochemical and in situ hybridization.
KECK LABORATORY FOR INTEGRATED BIOLOGY II (CHEMISTRY AND BIOCHEMISTRY)
(DR. ANDREW MCCAMMON)
Location: Room 2205, Urey Hall
Contact: Dr. Andrew McCammon ( amccammon@ucsd.edu ) (858: 534-2905)
This facility, a satellite of the San Diego Supercomputer Center , is a state of the art computational center.
KEVEX SYSTEM (RADIOLOGY)
(DR. ROBERT MATTREY)
Location: UCSD Medical Center-Hillcrest CT Scan Rooms
Contact: Rocelle Lambert ( rrlambert@ucsd.edu ) (619: 543-5705)
This service provides film processing and ultrasound scanning for minor and major experimental surgical procedures.
LIPID ANALYTIC LAB (MEDICINE)
(DR. JOSEPH WITZTUM)
Location: Room 128, Medical Teaching Facility
Contact: Dorothea Sisto ( dsisto@ucsd.edu ) (858: 822-1925)
This lab provides a variety of lipid analyses.
LIPIDOMICS CORE FACILITY (PHARMACOLOGY AND CHEMISTRY & BIOCHEMISTRY)
(DR. EDWARD A. DENNIS)
Location: Biochemical Signaling Suite, Room 4079, Basic Sciences Building
Contact: Dr. Richard Harkewicz ( rharkewicz@ucsd.edu ) (858: 822-5853)
This facility uses liquid chromatography-mass spectroscopy to analyze eicosanoids and related lipids fatty produced from activated macrophages as part of the LIPID MAPS Consortium.
LYMPHOCYTE PROLIFERATION ASSAY LAB (PATHOLOGY)
(DR. RACHEL SCHRIER)
Location: Rooms C401, C418, Clinical Teaching Facility, C Wing
Contact: Nikita Rochelle ( nrochelle@ucsd.edu ) (858: 822-0198)
This lab performs lymphocyte proliferation assays on blood obtained from HIV-infected patients to evaluate immune function.
MAGNETIC RESONANCE FACILITY (RADIOLOGY)
(DR. RICHARD BUXTON)
Location: UCSD Medical Centers – Hillcrest, Thornton
Contact: Wei Deng ( wedeng@ucsd.edu ) (858: 822-0527)
This facility provides magnetic resonance imaging services.
MASS SPECTROMETRIC FACILITY (CHEMISTRY AND BIOCHEMISTRY, PHARMACOLOGY)
(DR. ELIZABETH KOMIVES; DR. ROBERT TUKEY)
Location: 2245 Urey Hall
Contact: Dr. Elizabeth Komives ( ekomives@ucsd.edu ) (858: 534-3058); Dr. Robert
Tukey ( rtukey@ucsd.edu ) (858: 822-0288); Michelle Feiock
( mfeiock@ucsd.edu ) (858: 822-0286)
This facility provides mass spectrometric analyses. The instrumentation includes a high-resolution MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) spectrometer (E132).
MICROBIOLOGY LABORATORY SERVICES (PATHOLOGY)
(DR. SHARON L. REED)
Location: UCSD Medical Center – Hillcrest
Contact: Judy Tieber ( jtieber@ucsd.edu ) (858: 534-4325)
These services include bacteriology, virology, serology, parasitology, and mycology.
MITOCHONDRIAL DNA LAB (NEUROSCIENCES)
(DR. WILLIAM NYHAN)
Location: Room 203, 220 West Dickinson Street (UCSD Medical Center-Hillcrest)
Contact: Mike Bartel ( mbartel@ucsd.edu ) (858: 534-8854)
This lab performs a mitochondrial DNA panel and Southern blot analysis.
MOLECULAR BIOLOGY CORE FACILITY (MEDICINE)
(DR. DAVID LOONEY)
Location: Room 302, Stein Clinical Sciences Building
Contact: Dr. David Looney ( dlooney@ucsd.edu ) (858: 552-8585, X2626)
This facility provides molecular biology services for AIDS research.
MOLECULAR BIOLOGY CORE FACILITY (MEDICINE-RDCC)
(DR. GREGG SILVERMAN)
Location: Rooms 106, 108A, Stein Clinical Sciences Building
Contact: Dr. Gregg Silverman ( gsilverman@ucsd.edu ) (858: 534-5439)
This facility provides consultation and technical services in molecular biology of rheumatic diseases.
MOLECULAR PATHOLOGY CORE FACILITY ( CANCER CENTER )
(DR. LINDA WASSERMAN)
Location: Building 7, The Burnham Institute
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This facility provides laser-capture microdissection, cutting, histochemical staining, and analysis of frozen tissue sections.
MOUSE HEMATOLOGY AND CHEMISTRY LAB (PATHOLOGY)
(DR. DZUNG THE LE)
Location: Room 1023, Basic Sciences Building
Contact: Dr. Dzung The Le ( dzle@ucsd.edu ) (858: 534-8048)
This facility performs hematology, coagulation, anticoagulation, and chemistry analyses for the mouse.
MOUSE PHENOTYPE CORE FACILITY (CELLULAR & MOLECULAR MEDICINE)
(DR. JAMEY MARTH)
Location: CMM
Contact: Stephen Lopez ( slopez@ucsd.edu ) (858: 534-7710)
This facility provides mouse immunology services.
NEUROSCIENCE MICROSCOPY SHARED RESOURCE
(DR. JOSEPH GLEESON)
Location: CMM
Contact: B. Brinkman ( bcbrinkm@ucsd.edu ) (858: 534-0538)
This resource consists of a DeltaVision inverted microscope with temperature and carbon dioxide control for long-term time-lapse multichannel analysis. Its primary focus is on dissociated cell or cell culture fluorescent imaging. There is also an Olympus upright confocal microscope with two channel multiphoton addition, temperature and carbon dioxide controls for long-term time-lapse analysis. Its primary focus is on live thick-tissue sections using fluorescent imaging.
NEUROCYTOLOGY LAB (NEUROSCIENCES)
(DR. MARK ELLISMAN)
Location: Room 1000, Basic Sciences Building
Contact: Dolores Robinson ( d1robinson@ucsd.edu ) (858: 534-0276)
This lab provides specialized equipment and training for morphological research in cellular neurology.
NUCLEAR MAGNETIC RESONANCE FACILITY (CHEMISTRY AND BIOCHEMISTRY)
(DR. STANLEY OPELLA)
Location: Natural Sciences Building
Contact: Dr. Stanley Opella ( sopella@ucsd.edu ) (858: 822-4820)
This resource provides analysis of molecular and macromolecular structure.
NUTRITION CORE FACILITY ( CANCER CENTER )
(DR. CHERYL ROCK)
Location: 8950 Villa La Jolla ( La Jolla Professional Center )
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This facility provides dietary assessment and monitoring as well as laboratory evaluation using biomarker measurements. Dietary counseling is also provided.
OLIGONUCLEOTIDE SYNTHESIS FACILITY (CELLULAR & MOLECULAR MEDICINE)
(DR. LAWRENCE GOLDSTEIN)
Location: Room 244, CMM-West
Contact: Stephen Lopez ( slopez@ucsd.edu ) (858: 534-7710)
This facility provides oligonucleotides of a specific sequence as requested by investigators.
ORGAN AND BONE MARROW TRANSPLANT TESTING (PATHOLOGY)
(DR. LAURALYN LEBECK)
Location: Whittier Building , 9894 Genesee , Suite 101
Contact: Judy Tieber ( jtieber@ucsd.edu ) (858: 534-4325)
This facility provides transplantation immunology services, HLA typing, and flow cytometric services.
PHARMACOLOGY SERVICES UNIT ( CANCER CENTER )
(DR. STEPHEN HOWELL)
Location: UC 303
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This unit provides measurement of drug levels, assay development, pharmacokinetic modeling, and quality control studies.
PROTEIN CRYSTALLOGRAPHIC FACILITY (BIOLOGICAL SCIENCES)
(DR. XUONG NGUYEN-HUU)
Location: 5132 Urey Hall
Contact: Dr. Xuong Nguyen-Huu (858: 534-2501)
This facility includes two high-speed data-collection systems set up on the two windows of a very high brilliance FR x-ray generator.
RADIATION MEDICINE UNIT ( CANCER CENTER )
(DR. FRANCISCO PARDO)
Location: B-167
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This unit provides radiation facilities and radiobiologic expertise.
RADIOIMMUNOASSAY LAB (VA MEDICAL CENTER ) (MEDICINE)
(DR. LEONARD DEFTOS)
Location: Veterans Affairs San Diego Healthcare System
Contact: Dorothea Sisto ( dsisto@ucsd.edu ) (858: 822-1925)
This lab provides analysis of parathormone and calcitonin.
REPRODUCTIVE ENDOCRINOLOGY LAB (REPRODUCTIVE MEDICINE)
(DR. R. JEFFREY CHANG)
Location: Room 5039, Basic Sciences Building
Contact: Charito Jimenez ( casimon@ucsd.edu ) (619: 543-3492)
This andrology portion of this lab performs semen analysis and sperm preparation. The hormone assay section provides measurements of protein and steroid hormones.
SMALL-MOLECULE X-RAY FACILITY (CHEMISTRY AND BIOCHEMISTRY)
(DR. ARNOLD RHEINGOLD)
Location: 5018 Pacific Hall
Contact: Dr. Arnold Rheingold ( arheingold@ucsd.edu ) (858: 822-3870)
This facility provides complete crystallographic and molecular structural analysis on inorganic and organic compounds.
TRANSGENIC MOUSE FACILITY ( CANCER CENTER )
(DR. PAMELA MELLON)
Location: Vivarium, CMM-East
Contact: Sonia Ashley ( scashley@ucsd.edu ) (858: 822-0474)
This facility provides transgenic and knockout mice to researchers.
TRANSGENIC MOUSE FACILITY (CELLULAR & MOLECULAR MEDICINE)
(DR. JAMEY MARTH)
Location: Rooms 1022, 1023, CMM-East
Contact: Stephen Lopez ( slopez@ucsd.edu ) (858: 534-7710)
This facility prepares transgenic mice with specific genetic alterations that will produce offspring with the same specific alteration.
VECTOR DEVELOPMENT LAB (GENE THERAPY PROGRAM)
(DR. THEODORE FRIEDMAN)
Location: Rooms 2020A, 2004, CMM-East
Contact: Kathryn Bouic ( kbouic@ucsd.edu ) (858: 534-5245)
This lab develops and produces gene-transfer materials for use in preclinical studies with potential for gene therapy applications.
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